Neutralizing Effects of Small Molecule Inhibitors and Metal Chelators on Coagulopathic <i>Viperinae</i> Snake Venom Toxins

Neutralizing Effects of Small Molecule Inhibitors and Metal Chelators on Coagulopathic <i>Viperinae</i> Snake Venom Toxins

Animal-derived antivenoms are the only specific therapies currently available for the treatment of snake envenoming, but these products have a number of limitations associated with their efficacy, safety and affordability for use in tropical snakebite victims. Small molecule drugs and drug candidate...

Full description

Bibliographic Details
Main Authors: Chunfang Xie, Laura-Oana Albulescu, Mátyás A. Bittenbinder, Govert W. Somsen, Freek J. Vonk, Nicholas R. Casewell, Jeroen Kool
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biomedicines
Subjects:
snakebite treatments
marimastat
varespladib
dimercaprol
DMPS
nanofractionation
Online Access:https://www.mdpi.com/2227-9059/8/9/297

Internet

https://www.mdpi.com/2227-9059/8/9/297

Similar Items