Safety and efficacy of tuberculosis vaccine candidates in low- and middle-income countries: a systematic review of randomised controlled clinical trials

Safety and efficacy of tuberculosis vaccine candidates in low- and middle-income countries: a systematic review of randomised controlled clinical trials

Abstract Background Tuberculosis (TB) remains a leading cause of death worldwide, with 98% of cases occurring in low- and middle-income countries (LMICs). The only vaccine licenced for the prevention of TB has limited protection for adolescents, adults and vulnerable populations. A safe and effectiv...

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Bibliographic Details
Main Authors: Lydia Wilson, Lara Gracie, Farah Kidy, G. Neil Thomas, Krishnarajah Nirantharakumar, Sheila Greenfield, Semira Manaseki-Holland, Derek J. Ward, Tiffany E. Gooden
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Infectious Diseases
Subjects:
Tuberculosis
Vaccine safety
Vaccine efficacy
Infectious disease control
Clinical trials
Online Access:https://doi.org/10.1186/s12879-023-08092-4

Internet

https://doi.org/10.1186/s12879-023-08092-4

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