Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis

Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis

Summary: The fungal pathogen Candida albicans is linked to chronic brain diseases such as Alzheimer’s disease (AD), but the molecular basis of brain anti-Candida immunity remains unknown. We show that C. albicans enters the mouse brain from the blood and induces two neuroimmune sensing mechanisms in...

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Váldodahkkit: Yifan Wu, Shuqi Du, Lynn H. Bimler, Kelsey E. Mauk, Léa Lortal, Nessim Kichik, James S. Griffiths, Radim Osicka, Lizhen Song, Katherine Polsky, Lydia Kasper, Peter Sebo, Jill Weatherhead, J. Morgan Knight, Farrah Kheradmand, Hui Zheng, Jonathan P. Richardson, Bernhard Hube, Julian R. Naglik, David B. Corry
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Elsevier 2023-10-01
Ráidu:Cell Reports
Fáttát:
CP: Neuroscience
CP: Immunology
Liŋkkat:http://www.sciencedirect.com/science/article/pii/S2211124723012524

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http://www.sciencedirect.com/science/article/pii/S2211124723012524

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