Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation during Drosophila development

Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation during Drosophila development

Mature microRNAs (miRNAs) are processed from primary transcripts (pri-miRNAs), and their expression is controlled at transcriptional and post-transcriptional levels. However, how regulation at multiple levels achieves precise control remains elusive. Using published and new datasets, we profile a ti...

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Bibliographic Details
Main Authors: Li Zhou, Mandy Yu Theng Lim, Prameet Kaur, Abil Saj, Diane Bortolamiol-Becet, Vikneswaran Gopal, Nicholas Tolwinski, Greg Tucker-Kellogg, Katsutomo Okamura
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-07-01
Series:eLife
Subjects:
gene expression
miRNA stability
clustered miRNA genes
embryogenesis
Online Access:https://elifesciences.org/articles/38389

Internet

https://elifesciences.org/articles/38389

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