Range of chromatin accessibility configurations are permissive of GABAergic fate acquisition in developing mouse brain

Abstract In recent single-cell -omics studies, both the differential activity of transcription factors regulating cell fate determination and differential genome activation have been tested for utility as descriptors of cell types. Naturally, genome accessibility and gene expression are interlinked....

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Bibliographic Details
Main Authors: Sami Kilpinen, Heidi Heliölä, Kaia Achim
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-023-09836-x