A highly sensitive colorimetric approach based on tris (bipyridine) Ruthenium (II/III) mediator for the enzymatic detection of phenylalanine

A highly sensitive colorimetric approach based on tris (bipyridine) Ruthenium (II/III) mediator for the enzymatic detection of phenylalanine

The accurate monitoring of phenylalanine concentration plays a prominent role in the treatment of phenylketonuria (PKU). In this study, we present an enzymatic assay based on Phenylalanine Dehydrogenase/NAD+ and tris (bipyridine) Ruthenium (II/III) as a colorimetric mediator for the detection of Phe...

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Bibliographic Details
Main Authors: Maria Anna Messina, Ludovica Maugeri, Giuseppe Forte, Martino Ruggieri, Salvatore Petralia
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Chemistry
Subjects:
phenylalanine
enzymatic-sensing
phenylketonuria
tris (bipyridine) Ruthenium (II/III)
colorimetric-assay
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2023.1164014/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2023.1164014/full

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