Regioselective Hydroxylation of Rhododendrol by CYP102A1 and Tyrosinase

Rhododendrol (RD) is a naturally occurring phenolic compound found in many plants. Tyrosinase (Ty) converts RD to RD-catechol and subsequently RD-quinone via two-step oxidation reactions, after which RD-melanin forms spontaneously from RD-quinone. RD is cytotoxic in melanocytes and lung cancer cells...

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Bibliographic Details
Main Authors: Chan Mi Park, Hyun Seo Park, Gun Su Cha, Ki Deok Park, Chul-Ho Yun
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Catalysts
Subjects:
Online Access:https://www.mdpi.com/2073-4344/10/10/1114