Identification of crucial amino acid residues involved in large ring cyclodextrin synthesis by amylomaltase from Corynebacterium glutamicum

Identification of crucial amino acid residues involved in large ring cyclodextrin synthesis by amylomaltase from Corynebacterium glutamicum

Amylomaltase can be used to synthesize large ring cyclodextrins (LR-CDs), applied as drug solubilizer, gene delivery vehicle and protein aggregation suppressor. This study aims to determine the functional amino acid positions of Corynebacterium glutamicum amylomaltase (CgAM) involved in LR-CD synthe...

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Bibliographic Details
Main Authors: Sirikul Ngawiset, Abbas Ismail, Shuichiro Murakami, Piamsook Pongsawasdi, Thanyada Rungrotmongkol, Kuakarun Krusong
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Amylomaltase
Corynebacterium glutamicum
Large-ring cyclodextrin
Molecular dynamic simulation
Site-directed mutagenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037023000090

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http://www.sciencedirect.com/science/article/pii/S2001037023000090

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