Anionic phospholipids control mechanisms of GPCR-G protein recognition

Anionic phospholipids control mechanisms of GPCR-G protein recognition

In cell membranes, lipids are ubiquitous regulators of protein function. Here, Thakur et al. observe anionic phospholipids impact the conformational dynamics of a class A human GPCR.

Bibliographic Details
Main Authors: Naveen Thakur, Arka P. Ray, Liam Sharp, Beining Jin, Alexander Duong, Niloofar Gopal Pour, Samuel Obeng, Anuradha V. Wijesekara, Zhan-Guo Gao, Christopher R. McCurdy, Kenneth A. Jacobson, Edward Lyman, Matthew T. Eddy
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36425-z

Internet

https://doi.org/10.1038/s41467-023-36425-z

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