Human neuronal cells: epigenetic aspects

Human neuronal cells: epigenetic aspects

Histone acetyltransferases (HATs) and histone deacetylases (HDACs) promote histone posttranslational modifications, which lead to an epigenetic alteration in gene expression. Aberrant regulation of HATs and HDACs in neuronal cells results in pathological consequences such as neurodegeneration. Alzhe...

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Bibliographic Details
Main Authors: Kukucka Jessica, Wyllie Tessa, Read Justin, Mahoney Lauren, Suphioglu Cenk
Format: Article
Language:English
Published: De Gruyter 2013-08-01
Series:Biomolecular Concepts
Subjects:
acetylation
alzheimer’s disease
deacetylation
gene expression
neuroprotection
neurotoxicity
Online Access:https://doi.org/10.1515/bmc-2012-0053

Internet

https://doi.org/10.1515/bmc-2012-0053

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