Endometriotic lesions exhibit distinct metabolic signature compared to paired eutopic endometrium at the single-cell level

Endometriotic lesions exhibit distinct metabolic signature compared to paired eutopic endometrium at the single-cell level

Abstract Current therapeutics of endometriosis focus on hormonal disruption of endometriotic lesions (ectopic endometrium, EcE). Recent findings show higher glycolysis utilization in EcE, suggesting non-hormonal strategy for disease treatment that addresses cellular metabolism. Identifying metabolic...

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Bibliographic Details
Main Authors: Meruert Sarsenova, Ankita Lawarde, Amruta D. S. Pathare, Merli Saare, Vijayachitra Modhukur, Pille Soplepmann, Anton Terasmaa, Tuuli Käämbre, Kristina Gemzell-Danielsson, Parameswaran Grace Luther Lalitkumar, Andres Salumets, Maire Peters
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-06713-5

Internet

https://doi.org/10.1038/s42003-024-06713-5

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