JAK2 in Myeloproliferative Neoplasms: Still a Protagonist

The discovery of the activating V617F mutation in Janus kinase 2 (JAK2) has been decisive for the understanding of myeloproliferative neoplasms (MPN). Activated JAK2 signaling by <i>JAK2</i>, <i>CALR,</i> and <i>MPL</i> mutations has become a focus for the develop...

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Bibliographic Details
Main Authors: Michael Stephan Bader, Sara Christina Meyer
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/15/2/160