Probing the interaction of the diarylquinoline TMC207 with its target mycobacterial ATP synthase.

Probing the interaction of the diarylquinoline TMC207 with its target mycobacterial ATP synthase.

Infections with Mycobacterium tuberculosis are substantially increasing on a worldwide scale and new antibiotics are urgently needed to combat concomitantly emerging drug-resistant mycobacterial strains. The diarylquinoline TMC207 is a highly promising drug candidate for treatment of tuberculosis. T...

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Bibliographic Details
Main Authors: Anna C Haagsma, Ioana Podasca, Anil Koul, Koen Andries, Jerome Guillemont, Holger Lill, Dirk Bald
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3157398?pdf=render

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http://europepmc.org/articles/PMC3157398?pdf=render

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