Inspecting the Ribozyme Region of Hepatitis Delta Virus Genotype 1: Conservation and Variability

Inspecting the Ribozyme Region of Hepatitis Delta Virus Genotype 1: Conservation and Variability

The hepatitis delta virus (HDV) genome has an autocatalytic region called the ribozyme, which is essential for viral replication. The aim of this study was to use next-generation sequencing (NGS) to analyze the ribozyme quasispecies (QS) in order to study its evolution and identify highly conserved...

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Bibliographic Details
Main Authors: Beatriz Pacin-Ruiz, María Francesca Cortese, David Tabernero, Sara Sopena, Josep Gregori, Selene García-García, Rosario Casillas, Adrián Najarro, Unai Aldama, Adriana Palom, Ariadna Rando-Segura, Anna Galán, Marta Vila, Mar Riveiro-Barciela, Josep Quer, Gloria González-Aseguinolaza, María Buti, Francisco Rodríguez-Frías
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Viruses
Subjects:
hepatitis delta virus
ribozyme
next-generation sequencing
quasispecies
conservation
variability
Online Access:https://www.mdpi.com/1999-4915/14/2/215

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https://www.mdpi.com/1999-4915/14/2/215

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