Isoquinolone Synthesis via Zn(OTf)<sub>2</sub>-Catalyzed Aerobic Cyclocondensation of 2-(1-Alkynyl)-benzaldehydes with Arylamines
A zinc(II) triflate-catalyzed cyclocondensation of <i>ortho</i>-alkynylbenzaldehydes with arylamines in the presence of base under an oxygen atmosphere affording isoquinolones in good to high yields has been developed. The advantages of the present catalyst system include the use of an a...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-06-01
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| Series: | Catalysts |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4344/10/6/683 |