MRI-derived radiomics assessing tumor-infiltrating macrophages enable prediction of immune-phenotype, immunotherapy response and survival in glioma

MRI-derived radiomics assessing tumor-infiltrating macrophages enable prediction of immune-phenotype, immunotherapy response and survival in glioma

Abstract Background The tumor immune microenvironment can influence the prognosis and treatment response to immunotherapy. We aimed to develop a non-invasive radiomic signature in high-grade glioma (HGG) to predict the absolute density of tumor-associated macrophages (TAMs), the preponderant immune...

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Bibliographic Details
Main Authors: Di Chen, Rui Zhang, Xiaoming Huang, Chunxia Ji, Wei Xia, Ying Qi, Xinyu Yang, Lishuang Lin, Jing Wang, Haixia Cheng, Weijun Tang, Jinhua Yu, Dave S. B. Hoon, Jun Zhang, Xin Gao, Yu Yao
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Biomarker Research
Subjects:
Glioma
Magnetic resonance imaging
Radiomics
Macrophages
Immunotherapy
Prognosis
Online Access:https://doi.org/10.1186/s40364-024-00560-6

Internet

https://doi.org/10.1186/s40364-024-00560-6

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