miRNA-27a is essential for bone remodeling by modulating p62-mediated osteoclast signaling

The ability to simultaneously modulate a set of genes for lineage-specific development has made miRNA an ideal master regulator for organogenesis. However, most miRNA deletions do not exhibit obvious phenotypic defects possibly due to functional redundancy. miRNAs are known to regulate skeletal line...

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Bibliographic Details
Main Authors: Shumin Wang, Eri O Maruyama, John Martinez, Justin Lopes, Trunee Hsu, Wencheng Wu, Wei Hsu, Takamitsu Maruyama
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/79768