miRNA-27a is essential for bone remodeling by modulating p62-mediated osteoclast signaling
The ability to simultaneously modulate a set of genes for lineage-specific development has made miRNA an ideal master regulator for organogenesis. However, most miRNA deletions do not exhibit obvious phenotypic defects possibly due to functional redundancy. miRNAs are known to regulate skeletal line...
Main Authors: | Shumin Wang, Eri O Maruyama, John Martinez, Justin Lopes, Trunee Hsu, Wencheng Wu, Wei Hsu, Takamitsu Maruyama |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2023-02-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/79768 |
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