Structural basis of ribosomal RNA transcription regulation
Ribosomal RNA (rRNA) expression is regulated at the initiation stage of RNA synthesis. Here, the authors report cryo-EM structures of E. coli RNA polymerase and rRNA promoter complex with DksA/ppGpp on the way to open complex formation, identifying key steps in promoter recognition and opening.
Päätekijät: | , , , , , |
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Aineistotyyppi: | Artikkeli |
Kieli: | English |
Julkaistu: |
Nature Portfolio
2021-01-01
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Sarja: | Nature Communications |
Linkit: | https://doi.org/10.1038/s41467-020-20776-y |