Analysis of IL28B variants in an Egyptian population defines the 20 kilobases minimal region involved in spontaneous clearance of hepatitis C virus.

Analysis of IL28B variants in an Egyptian population defines the 20 kilobases minimal region involved in spontaneous clearance of hepatitis C virus.

Spontaneous clearance of hepatitis C virus (HCV) occurs in ~30% of acute infections. Host genetics play a major role in HCV clearance, with a strong effect of single nucleotide polymorphisms (SNPs) of the IL28B gene already found in different populations, mostly infected with viral genotypes 1 and 3...

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Main Authors: Vincent Pedergnana, Mohamed Abdel-Hamid, Julien Guergnon, Amira Mohsen, Lénaïg Le Fouler, Ioannis Theodorou, Mostafa Kamal Mohamed, Arnaud Fontanet, Sabine Plancoulaine, Laurent Abel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3375300?pdf=render

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http://europepmc.org/articles/PMC3375300?pdf=render

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