Akt2- and ETS1-Dependent IP3 Receptor 2 Expression in Dendritic Cell Migration

Akt2- and ETS1-Dependent IP3 Receptor 2 Expression in Dendritic Cell Migration

Background/Aims: The protein kinase Akt2/PKBβ is a known regulator of macrophage and dendritic cell (DC) migration. The mechanisms linking Akt2 activity to migration remained, however, elusive. DC migration is governed by Ca2+ signaling. We thus explored whether Akt2 regulates DC Ca2+ signaling. Met...

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Bibliographic Details
Main Authors: Wenting Yang, Meerim K. Nurbaeva, Evi Schmid, Antonella Russo, Ahmad Almilaji, Kalina Szteyn, Jing Yan, Caterina Faggio, Ekaterina Shumilina, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
CCL21
Ca2+ release
ICRAC
SOCE
Online Access:http://www.karger.com/Article/FullText/356664

Internet

http://www.karger.com/Article/FullText/356664

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