scMoMaT jointly performs single cell mosaic integration and multi-modal bio-marker detection

Many methods for single cell data integration have been developed, though mosaic integration remains challenging. Here the authors present scMoMaT, a mosaic integration method for single cell multi-modality data from multiple batches, that jointly learns cell representations and marker features acro...

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Bibliographic Details
Main Authors: Ziqi Zhang, Haoran Sun, Ragunathan Mariappan, Xi Chen, Xinyu Chen, Mika S. Jain, Mirjana Efremova, Sarah A. Teichmann, Vaibhav Rajan, Xiuwei Zhang
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36066-2