A Critical Role for Perivascular Cells in Amplifying Vascular Leakage Induced by Dengue Virus Nonstructural Protein 1
ABSTRACT Dengue is the most prevalent arthropod-borne viral disease affecting humans, with severe dengue typified by potentially fatal microvascular leakage and hypovolemic shock. Blood vessels of the microvasculature are composed of a tubular structure of endothelial cells ensheathed by perivascula...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2020-08-01
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Series: | mSphere |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mSphere.00258-20 |