Murine Models Provide New Insights Into Pathogenesis of Chronic Graft-Versus-Host Disease in Humans

Allogeneic hematopoietic cell transplantation (allo-HCT) is a curative therapy for hematologic malignancies, but its success is complicated by graft-versus-host disease (GVHD). GVHD can be divided into acute and chronic types. Acute GVHD represents an acute alloimmune inflammatory response initiated...

Full description

Bibliographic Details
Main Authors: Qingxiao Song, Xiaohui Kong, Paul J. Martin, Defu Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.700857/full