Glioblastoma cells increase expression of notch signaling and synaptic genes within infiltrated brain tissue

Glioblastoma cells increase expression of notch signaling and synaptic genes within infiltrated brain tissue

Abstract Glioblastoma remains one of the deadliest brain malignancies. First-line therapy consists of maximal surgical tumor resection, accompanied by chemotherapy and radiotherapy. Malignant cells escape surgical resection by migrating into the surrounding healthy brain tissue, where they give rise...

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Bibliographic Details
Main Authors: Dylan Scott Lykke Harwood, Vilde Pedersen, Nicolai Schou Bager, Ane Yde Schmidt, Tobias Overlund Stannius, Aušrinė Areškevičiūtė, Knud Josefsen, Dorte Schou Nørøxe, David Scheie, Hannah Rostalski, Maya Jeje Schuang Lü, Alessio Locallo, Ulrik Lassen, Frederik Otzen Bagger, Joachim Weischenfeldt, Dieter Henrik Heiland, Kristoffer Vitting-Seerup, Signe Regner Michaelsen, Bjarne Winther Kristensen
Format: Article
Language:English
Published: Nature Portfolio 2024-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-52167-y

Internet

https://doi.org/10.1038/s41467-024-52167-y

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