Use of a Primary Epithelial Cell Screening Tool to Investigate Phage Therapy in Cystic Fibrosis

Use of a Primary Epithelial Cell Screening Tool to Investigate Phage Therapy in Cystic Fibrosis

Antimicrobial-resistant microbes are an increasing threat to human health. In cystic fibrosis (CF), airway infections with Pseudomonas aeruginosa remain a key driver of lung damage. With few new antibiotics on the development horizon, alternative therapeutic approaches are needed against antimicrobi...

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Bibliographic Details
Main Authors: Stephanie Trend, Barbara J. Chang, Mark O’Dea, Stephen M. Stick, Anthony Kicic, WAERP, AusREC, AREST CF
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Pharmacology
Subjects:
cystic fibrosis
phage therapy
preclinical models
airway epithelial cells
Pseudomonas aeruginosa
infection
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01330/full

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https://www.frontiersin.org/article/10.3389/fphar.2018.01330/full

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