Fabrication of a Controlled-Release Core-Shell Floating Tablet of Ketamine Hydrochloride Using a 3D Printing Technique for Management of Refractory Depressions and Chronic Pain

Fabrication of a Controlled-Release Core-Shell Floating Tablet of Ketamine Hydrochloride Using a 3D Printing Technique for Management of Refractory Depressions and Chronic Pain

In this study, a novel floating, controlled-release and core-shell oral tablet of ketamine hydrochloride (HCl) was produced using a dual extrusion by 3D printing method. A mixture of Soluplus<sup>®</sup> and Eudragit<sup>®</sup> RS-PO was extruded by a hot-melt extrusion (HME...

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Bibliographic Details
Main Authors: Tahmineh Karami, Emad Ghobadi, Mohammad Akrami, Ismaeil Haririan
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Polymers
Subjects:
3D printing
additive manufacturing
ketamine
tablet
extended release
personalized medicine
Online Access:https://www.mdpi.com/2073-4360/16/6/746

Internet

https://www.mdpi.com/2073-4360/16/6/746

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