G-Protein-Coupled Receptor (GPCR) Signaling in the Carotid Body: Roles in Hypoxia and Cardiovascular and Respiratory Disease

G-Protein-Coupled Receptor (GPCR) Signaling in the Carotid Body: Roles in Hypoxia and Cardiovascular and Respiratory Disease

The carotid body (CB) is an important organ located at the carotid bifurcation that constantly monitors the blood supplying the brain. During hypoxia, the CB immediately triggers an alarm in the form of nerve impulses sent to the brain. This activates protective reflexes including hyperventilation,...

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Bibliographic Details
Main Authors: Hayyaf S. Aldossary, Abdulaziz A. Alzahrani, Demitris Nathanael, Eyas A. Alhuthail, Clare J. Ray, Nikolaos Batis, Prem Kumar, Andrew M. Coney, Andrew P. Holmes
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
G-protein
GPCR
carotid body
hypoxia
hypertension
drug-discovery
Online Access:https://www.mdpi.com/1422-0067/21/17/6012

Internet

https://www.mdpi.com/1422-0067/21/17/6012

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