Generation of Inheritable A-to-G Transitions Using Adenine Base Editing and NG-PAM Cas9 in Arabidopsis thaliana
Towards precise genome editing, base editors have been developed by fusing catalytically compromised Cas9 with deaminase components, mediating C-to-T (cytosine base editors) or A-to-G (adenine base editors) transition. We developed a set of vectors consisting of a 5′-NG-3′ PAM-recognizing variant of...
| मुख्य लेखकों: | , , , , , , , , , , |
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| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
The American Phytopathological Society
2025-01-01
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| श्रृंखला: | Molecular Plant-Microbe Interactions |
| विषय: | |
| ऑनलाइन पहुंच: | https://apsjournals.apsnet.org/doi/10.1094/MPMI-10-24-0127-TA |