Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia

Stearoyl-CoA desaturase (SCD) is expressed at high levels in several human tissues and is required for the biosynthesis of oleate (18:1) and palmitoleate (16:1). These monounsaturated fatty acids are the major components of phospholipids, triglycerides, wax esters, and cholesterol esters. Mice with...

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Bibliographic Details
Main Authors: Alan D. Attie, Ronald M. Krauss, Mark P. Gray-Keller, Alison Brownlie, Makoto Miyazaki, John J. Kastelein, Aldons J. Lusis, Anton F.H. Stalenhoef, Jonathan P. Stoehr, Michael R. Hayden, James M. Ntambi
Format: Article
Language:English
Published: Elsevier 2002-11-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520327656