ApoA-I Nanoparticles as Curcumin Carriers for Cerebral Endothelial Cells: Improved Cytoprotective Effects against Methylglyoxal

ApoA-I Nanoparticles as Curcumin Carriers for Cerebral Endothelial Cells: Improved Cytoprotective Effects against Methylglyoxal

Methylglyoxal (MGO) is a highly reactive metabolite of glucose present at elevated levels in diabetic patients. Its cytotoxicity is associated with endothelial dysfunction, which plays a role in cardiovascular and cerebrovascular complications. Although curcumin has many therapeutic benefits, these...

Full description

Bibliographic Details
Main Authors: Sai Sandhya Narra, Sarah Rosanaly, Philippe Rondeau, Jessica Patche, Bryan Veeren, Marie-Paule Gonthier, Wildriss Viranaicken, Nicolas Diotel, Palaniyandi Ravanan, Christian Lefebvre d’ Hellencourt, Olivier Meilhac
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Pharmaceuticals
Subjects:
nanoparticle
curcumin
HDL
methylglyoxal
cerebral endothelial cells
endothelial dysfunction
Online Access:https://www.mdpi.com/1424-8247/15/3/347

Internet

https://www.mdpi.com/1424-8247/15/3/347

Similar Items