Detection of 13C labeling of glutamate and glutamine in human brain by proton magnetic resonance spectroscopy

Abstract A proton magnetic resonance spectroscopy (MRS) technique was used to measure 13C enrichments of glutamate and glutamine in a 3.5 × 1.8 × 2 cm3 voxel placed in the dorsal anterior cingulate cortex of five healthy participants after oral administration of [U-13C]glucose. Strong pseudo singlet...

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Bibliographic Details
Main Authors: Li An, Shizhe Li, Maria Ferraris Araneta, Christopher S. Johnson, Jun Shen
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-12654-y