The Stroma Liquid Biopsy Panel Contains a Stromal-Epithelial Gene Signature Ratio That Is Associated with the Histologic Tumor-Stroma Ratio and Predicts Survival in Colon Cancer

The Stroma Liquid Biopsy Panel Contains a Stromal-Epithelial Gene Signature Ratio That Is Associated with the Histologic Tumor-Stroma Ratio and Predicts Survival in Colon Cancer

Liquid biopsy has emerged as a novel approach to tumor characterization, offering advantages in sample accessibility and tissue heterogeneity. However, as mutational analysis predominates, the tumor microenvironment has largely remained unacknowledged in liquid biopsy research. The current work prov...

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Bibliographic Details
Main Authors: Cor J. Ravensbergen, Matthew Kuruc, Meaghan Polack, Stijn Crobach, Hein Putter, Hans Gelderblom, Devjit Roy, Rob A. E. M. Tollenaar, Wilma E. Mesker
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
colon cancer
tumor microenvironment
tumor-stroma ratio
gene signature
liquid biopsy
Stroma Liquid Biopsy<sup>TM</sup>
Online Access:https://www.mdpi.com/2072-6694/14/1/163

Internet

https://www.mdpi.com/2072-6694/14/1/163

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