In vitro and in silico inhibition performance of choline against CYP1A2, CYP2D6 and CYP3A4

AbstractCholine is an essential nutrient involved in the synthesis of acetylcholine in the cholinergic neurons. The pharmacokinetic properties of choline are well described; however, there is a lack of data about its activity toward the CYP450 superfamily of enzymes. Therefore, the aim of this study...

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Bibliographic Details
Main Authors: Emilio Mateev, Antoaneta Balkanska-Mitkova, Lily Peikova, Maria Dimitrova, Magdalena Kondeva-Burdina
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/13102818.2022.2144452