Rosiglitazone Promotes Bone Marrow Adipogenesis to Impair Myelopoiesis under Stress.

OBJECTIVE:The therapeutic use of thiazolidinediones (TZDs) causes unwanted hematological side effects, although the underlying mechanisms of these effects are poorly understood. This study tests the hypothesis that rosiglitazone impairs the maintenance and differentiation of hematopoietic stem/proge...

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Bibliographic Details
Main Authors: Wenyi Lu, Weimin Wang, Shujuan Wang, Yonghuai Feng, Kaiyan Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4760757?pdf=render