ABHD12 contributes to tumorigenesis and sorafenib resistance by preventing ferroptosis in hepatocellular carcinoma

ABHD12 contributes to tumorigenesis and sorafenib resistance by preventing ferroptosis in hepatocellular carcinoma

Summary: Sorafenib induces ferroptosis, making it a useful treatment against advanced liver hepatocellular carcinoma (LIHC). However, sorafenib resistance is extremely common among LIHC patients. Here, we used a comprehensive approach to investigate the effects of ABHD12, which regulates tumorigenes...

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Bibliographic Details
Main Authors: Mengxing Cai, Jingwen Luo, Chunxiu Yang, Xiaopeng Yang, Cheng Zhang, Lixin Ma, Yibin Cheng
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:iScience
Subjects:
Pharmacology
Natural sciences
Biological sciences
Systems biology
Cancer systems biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223024173

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http://www.sciencedirect.com/science/article/pii/S2589004223024173

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