MYSTERY OF iAMP

Objective: Intrachromosomal amplification of chromosome 21 (iAMP21) is defined as the presence of three or more RUNX1 signals on a single chromosome, or a total of five or more RUNX1 signals per cell. It occurs in 2% of pediatric B-cell acute lymphoblastic leukemia (ALL), but is associated with olde...

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Bibliographic Details
Main Authors: Fatma Burçin KURTİPEK, Dilek KAÇAR, Ebru TUNÇEZ, Melek IŞIK, Neşe YARALI
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Hematology, Transfusion and Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S253113792101141X