Development of a depot formulation with an in situ non-lamellar liquid crystal-forming system with phospholipids

Development of a depot formulation with an in situ non-lamellar liquid crystal-forming system with phospholipids

Non-lamellar liquid crystal (NLLC) structures have gained increasing attention for the controlled release of entrapped drugs. In the present study, an in situ NLLC structure-forming depot formulation through contact with water was developed using a ternary mixture system of soya phosphatidyl choline...

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Bibliographic Details
Main Authors: Hiroaki Todo, Rina Niki, Akie Okada, Ibuki Narita, Kazuya Inamura, Ayu Ito, Shoko Itakura, Ichiro Hijikuro, Kenji Sugibayashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Drug Delivery
Subjects:
lipid-based depot formulation
in situ forming system
sustained release
non-lamellar liquid crystal
long-acting drug delivery system
Online Access:https://www.frontiersin.org/articles/10.3389/fddev.2023.1270584/full

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https://www.frontiersin.org/articles/10.3389/fddev.2023.1270584/full

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