Improving hematopoietic recovery through modeling and modulation of the mesenchymal stromal cell secretome

Improving hematopoietic recovery through modeling and modulation of the mesenchymal stromal cell secretome

Abstract Background Efficient and sustained hematopoietic recovery after hematopoietic stem cell or bone marrow transplantation is supported by paracrine signaling from specific subpopulations of mesenchymal stromal cells (MSCs). Here, we considered whether in vitro mechanopriming of human MSCs coul...

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Bibliographic Details
Main Authors: Frances D. Liu, Kimberley Tam, Novalia Pishesha, Zhiyong Poon, Krystyn J. Van Vliet
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stromal cells
Secretome
Mechanobiology
Hematopoietic recovery
Radiation injury
Online Access:http://link.springer.com/article/10.1186/s13287-018-0982-2

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http://link.springer.com/article/10.1186/s13287-018-0982-2

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