Effects of the PARP inhibitor Niraparib on the radiosensitivity of human lung and cervical cancer cells

Effects of the PARP inhibitor Niraparib on the radiosensitivity of human lung and cervical cancer cells

Objective: To investigate the effect of Niraparib, a clinically approved PARP inhibitor on the radiosensitivity of human lung and cervical cancer cells, and preliminarily explore the underlying mechanism. Methods: The human lung cancer cell line A549 and human cervical cancer cell line Siha were bot...

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Bibliographic Details
Main Authors: Yue Feng, Shiyi Pi, Yuwei Li, Yu Zhang, Hongwei Zeng, E. Xiangyu, Yang Zhang, Jingping Yu
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Radiation Medicine and Protection
Subjects:
DNA damage repair
PARP inhibitor
Radiation therapy
Radiosensitivity
Tumor
Online Access:http://www.sciencedirect.com/science/article/pii/S2666555723000229

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http://www.sciencedirect.com/science/article/pii/S2666555723000229

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