Self-Organizing Maps for Cellular In Silico Staining and Cell Substate Classification

Cellular composition and structural organization of cells in the tissue determine effective antitumor response and can predict patient outcome and therapy response. Here we present Seg-SOM, a method for dimensionality reduction of cell morphology in H&E-stained tissue images. Seg-SOM resolve...

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Bibliographic Details
Main Authors: Edwin Yuan, Magdalena Matusiak, Korsuk Sirinukunwattana, Sushama Varma, Łukasz Kidziński, Robert West
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.765923/full