Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction
Collagens are a primary component of the extracellular matrix and are functional ligands for the inhibitory immune receptor leukocyte-associated immunoglobulin-like receptor (LAIR)-1. LAIR-2 is a secreted protein that can act as a decoy receptor by binding collagen with higher affinity than LAIR-1....
Հիմնական հեղինակներ: | M Ines Pascoal Ramos, Linjie Tian, Emma J de Ruiter, Chang Song, Ana Paucarmayta, Akashdip Singh, Eline Elshof, Saskia V Vijver, Jahangheer Shaik, Jason Bosiacki, Zachary Cusumano, Christina Jensen, Nicholas Willumsen, Morten A Karsdal, Linda Liu, Sol Langermann, Stefan Willems, Dallas Flies, Linde Meyaard |
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Ձևաչափ: | Հոդված |
Լեզու: | English |
Հրապարակվել է: |
eLife Sciences Publications Ltd
2021-06-01
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Շարք: | eLife |
Խորագրեր: | |
Առցանց հասանելիություն: | https://elifesciences.org/articles/62927 |
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