The release of tryptase from mast cells promote tumor cell metastasis via exosomes

The release of tryptase from mast cells promote tumor cell metastasis via exosomes

Abstract Background Cancer cells release exosomes and can be taken up by mast cells (MCs), but the potential functional effects of MCs on tumor metastasis remain unknown. Method Exosomes were isolated from the lung adenocarcinoma cell line A549, and the uptake of PKH26-labeled exosomes by bone marro...

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Bibliographic Details
Main Authors: Hui Xiao, Mudan He, Guogang Xie, Yanan Liu, Yuxia Zhao, Xiong Ye, Xingjing Li, Min Zhang
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Cancer
Subjects:
Lung cancer
Exosomes
Mast cell
Tryptase
Angiogenesis
Online Access:http://link.springer.com/article/10.1186/s12885-019-6203-2

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http://link.springer.com/article/10.1186/s12885-019-6203-2

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