Depletion of Macrophages Improves Therapeutic Response to Gemcitabine in Murine Pancreas Cancer

Depletion of Macrophages Improves Therapeutic Response to Gemcitabine in Murine Pancreas Cancer

Background: The tumor microenvironment (TME) is composed of fibro-inflammatory cells and extracellular matrix (ECM) components. However, the exact contribution of the various TME compartments towards therapeutic response is unknown. Here, we aim to dissect the specific contribution of tumor-associat...

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Bibliographic Details
Main Authors: Soeren M. Buchholz, Robert G. Goetze, Shiv K. Singh, Christoph Ammer-Herrmenau, Frances M. Richards, Duncan I. Jodrell, Malte Buchholz, Patrick Michl, Volker Ellenrieder, Elisabeth Hessmann, Albrecht Neesse
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
pancreatic cancer
drug delivery
macrophages
chemoresistance
Online Access:https://www.mdpi.com/2072-6694/12/7/1978

Internet

https://www.mdpi.com/2072-6694/12/7/1978

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