Distribution dynamics of recombinant Lactobacillus in the gastrointestinal tract of neonatal rats.

One approach to deliver therapeutic agents, especially proteins, to the gastro-intestinal (GI) tract is to use commensal bacteria as a carrier. Genus Lactobacillus is an attractive candidate for use in this approach. However, a system for expressing exogenous proteins at a high level has been lackin...

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Bibliographic Details
Main Authors: Sujin Bao, Libin Zhu, Qiang Zhuang, Lucia Wang, Pin-Xian Xu, Keiji Itoh, Ian R Holzman, Jing Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3609735?pdf=render