Recruitment of a SAP18-HDAC1 complex into HIV-1 virions and its requirement for viral replication.

HIV-1 integrase (IN) is a virally encoded protein required for integration of viral cDNA into host chromosomes. INI1/hSNF5 is a component of the SWI/SNF complex that interacts with HIV-1 IN, is selectively incorporated into HIV-1 (but not other retroviral) virions, and modulates multiple steps, incl...

Full description

Bibliographic Details
Main Authors: Masha Sorin, Jennifer Cano, Supratik Das, Sheeba Mathew, Xuhong Wu, Kelvin P Davies, Xuanling Shi, S-W Grace Cheng, David Ott, Ganjam V Kalpana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19503603/?tool=EBI