Epidermal growth factor receptor in breast carcinoma: association between gene copy number and mutations

Epidermal growth factor receptor in breast carcinoma: association between gene copy number and mutations

<p>Abstract</p> <p>Background</p> <p>The epidermal growth factor receptor (EGFR) is an available target of effective anti-EGFR therapy for human breast cancer. The aim of this study was to assess the presence of EGFR gene amplification and mutations in breast cancer and...

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Bibliographic Details
Main Authors: Lv Ning, Xie Xiaoming, Ge Qidong, Lin Suxia, Wang Xi, Kong Yanan, Shi Hongliu, Xie Xinhua, Wei Weidong
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Diagnostic Pathology
Subjects:
breast cancer
epidermal growth factor receptor, EGFR
FISH
gene amplification
gene mutation
real-time PCR.
Online Access:http://www.diagnosticpathology.org/content/6/1/118

Internet

http://www.diagnosticpathology.org/content/6/1/118

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