Investigating the Prognostic Relevance of Tumor Immune Microenvironment and Immune Gene Assembly in Breast Carcinoma Subtypes

Investigating the Prognostic Relevance of Tumor Immune Microenvironment and Immune Gene Assembly in Breast Carcinoma Subtypes

We hypothesized that different BC subtypes are characterized by spatially distinct tumor immune microenvironment (TIME) and that immune gene assembly of metastatic (Met) and non-metastatic (Ctrl) BCs vary across subtypes. Peritumoral, stromal and intratumoral TIL was assessed on 309 BC cases. Hot, c...

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Bibliographic Details
Main Authors: Beáta Szeitz, Orsolya Pipek, Janina Kulka, Csilla Szundi, Orsolya Rusz, Tímea Tőkés, Attila Marcell Szász, Kristóf Attila Kovács, Adrián Pesti, Taya Beri Ben Arie, Ambrus Gángó, Zsolt Fülöp, Emőke Drágus, Stefan A. Vári-Kakas, Anna Mária Tőkés
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cancers
Subjects:
breast carcinoma subtypes
TIL
immune-related gene
NanoString
CD4<sup>+</sup> T cells
CD8<sup>+</sup> T cells
Online Access:https://www.mdpi.com/2072-6694/14/8/1942

Internet

https://www.mdpi.com/2072-6694/14/8/1942

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