Redistribution of the SWI/SNF Complex Dictates Coordinated Transcriptional Control over Epithelial–Mesenchymal Transition of Normal Breast Cells through TGF-β Signaling

Therapeutic targets in cancer cells defective for the tumor suppressor ARID1A are fundamentals of synthetic lethal strategies. However, whether modulating ARID1A function in premalignant breast epithelial cells could be exploited to reduce carcinogenic potential remains to be elucidated. In search o...

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Bibliographic Details
Main Authors: Sham Jdeed, Máté Lengyel, Iván P. Uray
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/17/2633