Growth differentiation factor-15, a novel systemic biomarker of oxidative stress, inflammation, and cellular aging: Potential role in cardiovascular diseases

Growth differentiation factor-15 (GDF-15) is a cytokine upregulated in multiple pathological conditions where oxidative stress, endothelial dysfunction, tissue aging, and chronic inflammation are the hallmarks. GDF-15 has many sources of production, including cardiac and vascular myocytes, endotheli...

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Bibliographic Details
Main Authors: Angelo Michele di Candia, Diane Xavier de Avila, Gustavo Rodolfo Moreira, Humberto Villacorta, Alan S. Maisel
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:American Heart Journal Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666602221000446